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Atherosclerosis Analysis
Project type
Biomedical Engineering
Date
Nov 2021 - Nov 2021
Skills
MATLAB
This project focuses on analyzing the biomechanics of atherosclerosis in the carotid artery. The goal is to derive mathematical models to understand the impact of atherosclerosis on blood flow and to calculate the necessary conditions for reducing vascular obstruction through interventions such as angioplasty with stenting.
Key Features:
- Atherosclerosis Analysis: Investigated the impact of atherosclerosis on the carotid artery, including the derivation of pressure differences using the Hagen-Poiseuille Law and the relationship between plaque length and height.
- Pressure and Diameter Relationship: Derived formulas to calculate the pressure increase (Δp) depending on the artery diameter (D1) and sketched the qualitative relationship between these variables.
- Plaque Length and Height Calculation: Calculated the length and height of atherosclerotic plaques based on given flow rates and pressures, and visualized the results on a graph.
- LV-PV Loops: Created LV-PV loops to represent healthy and stenosed artery states, marking key parameters such as EDV, ESV, SW, ESPVR, and EDPVR.
- Angioplasty Simulation: Analyzed the impact of angioplasty with stenting on reducing vascular obstruction and recalculated the pressure and diameter post-intervention.
